MagReSyn® Amine

Primary Amine functional support for ligand adsorption or chemical modification

Amine (NH2) functional microparticles may be used to physically adsorb biomolecules through ionic interaction, or they can be chemically functionalized for covalent coupling of biomolecules using a variety of bi-functional chemical coupling agents. The most frequently used coupling agents include glutaraldehyde and 1,4-butanediol diglycidyl ether.

For possible coupling chemistries and protocols we recommend you consult with the following reference: Hermanson, G.T. Bioconjugate Techniques, 2nd Edition, Academic Press Inc. (2008)

Support: Proprietary polymer microparticles containing iron oxide (magnetite)
Binding capacity: > 20 mg.ml-1 (BSA)
Bead size: ~5-10 µm
Formulation: 20 mg.ml-1 suspension in 20% ethanol

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Product Resources

MagReSyn® Amine Performance Superiority

Aldehyde-activated

Performance superiority of MagReSyn® Amine (green) functionalized for coupling with glutaraldehyde, compared to leading alternate suppliers’ supports (orange). Values used for alternate products are the respective suppliers’ claimed capacities.
GDH and NOD results obtained by Twala et al

Epoxide-activated

Performance superiority of MagReSyn® Amine (green) functionalized for coupling using epoxide activation, compared to leading alternate suppliers’ supports (orange). Values used for alternate products are the respective suppliers’ claimed capacities.
PyNP & PNP results obtained by Zhou et al

TERMS AND CONDITIONS
Products supplied by ReSyn Biosciences (Pty) Ltd are for research purposes only. ReSyn products are not to be used for diagnostic, therapeutic or commercial means any use resulting in monetary gain, including, but not limited to, incorporation in a kit, repackaging and re-formulation. Please enquire about sub-licenses for commercial use.

Citations and References

Sustainable synthesis of uridine-5′-monophosphate analogues by immobilized uracil phosphoribosyltransferase from Thermus thermophilus

–   Jon Del Arco et al.

BBA – Proteins and Proteomics, 1868 (2020)

MagReSyn® Amine (Aldehyde)

A Compact Quadrupole-Orbitrap Mass Spectrometer with FAIMS Interface Improves Proteome Coverage in Short LC Gradients

–   Dorte B. Bekker-Jensen et al.

Molecular and Cellular Proteomics (2020)

MagReSyn® Ti-IMAC HP & Amine

Structural and functional characterization of thermostable biocatalysts for the synthesis of 6-aminopurine nucleoside-5′-monophospate analogues

–   Jon Del Arco et al.

Bioresource Technology 276 (2019)

MagReSyn® Amine (Aldehyde)

Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives

– Jesús Fernández Lucas and María-José Camarasa Rius (Editors)

WILEY-VCH, October (2018)

MagReSyn® Amine

Enzymatic synthesis of therapeutic nucleosides using a highly versatile purine nucleoside 2′-deoxyribosyltransferase from Trypanosoma brucei

–   Elena Pérez et al.

ChemCatChem 10 (2018)

MagReSyn® Amine

One-Pot, One-Step Production of Dietary Nucleotides by Magnetic

–   Jon del Arco et al.

Catalysts 8 (2018)

MagReSyn® Amine

The co-immobilization of P450-type nitric oxide reductase and glucose dehydrogenase for the continuous reduction of nitric oxide via cofactor recycling

–   Seike Garny et al.

Enyzme & Microbial Technology 85 (2015)

MagReSyn® Carboxyl; MagReSyn® Amine (Epoxide)

Immobilization of thermostable nucleoside phosphorylases on MagReSyn® epoxide microspheres and their application for the synthesis of 2,6-dihalogenated purine nucleosides

–   Xinrui Zhou et al.

J. Mol. Cat. B: Enzymatic 115 (2015)

MagReSyn® Amine (Epoxide)

Synthesis of 2,6-dihalogenated purine nucleosides by thermostable nucleoside phosphorylases

–   Xinrui Zhou et al.

Advanced Synthesis & Catalysis 357 (2015)

MagReSyn® Amine (Epoxide)