Method Library

This resource aims to make methods more accessible to researchers, and help identify the most relevant methods for your current application. We would appreciate your participation in keeping this database up to date, so please report any errors such as broken links, missing information, or publications that are not included to info@resynbio.com.

Resource TitleYearSourceApplicationProductSampleStrategyExtractionClean-upDigestionQuantification
Liver-fibrosis-activated transcriptional networks govern hepatocyte reprogramming and intra-hepatic communication2021PublicationDigest preparationHILICMammalian tissueManualChaotropePrecipitation on-beadLysC, TrpLabel-free
The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3-Deficient Mouse Model of Achromatopsia2021PublicationPhosphopeptide enrichmentTi-IMACMammalian tissueManualN/APrecipitation in-solutionTrpLabel-free
Taylor-made production of pyrimidine nucleoside-5′-monophosphate analogues by highly stabilized mutant uracil phosphoribosyltransferase from Toxoplasma gondii2021PublicationImmobilizationAmine, Ni-NTAEnzymeN/AN/AN/AN/AN/A
New trends in the biocatalytic production of nucleosidic active pharmaceutical ingredients using 2′-deoxyribosyltransferases2021PublicationImmobilizationAmineEnzymeN/AN/AN/AN/AN/A
CDK8 Fine-Tunes IL-6 Transcriptional Activities by Limiting STAT3 Resident Time at the Gene Loci2021PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentPrecipitation in-solutionTrpMetabolic labelling
Spatial-proteomics reveal in-vivo phospho-signaling dynamics at subcellular resolution2021PublicationPhosphopeptide enrichment, Digest preparationTi-IMAC, AmineMammalian tissueAutomatedNative, DetergentPrecipitation on-beadLysC, TrpLabel-free
Identifying cytokine signaling signatures in primary human Th-1 cells by phospho-proteomics analysis2021PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentPrecipitation in-solutionTrpMetabolic labelling
Molecular roadmap of the healthy stress response in the mouse hippocampus2021PublicationPhosphopeptide enrichmentTi-IMACMammalian tissueManualDetergentFilter-basedTrpLabel-free
HNF4A is required to specify glucocorticoid action in the liver2021PublicationChIPProtein GMammalian tissueManualN/AN/AN/AN/A
Rapid auxin-mediated phosphorylation of Myosin regulates trafficking and polarity in Arabidopsis2021PublicationPhosphopeptide enrichmentTiO2, Ti-IMACPlant ManualDetergentHybridTrpLabel-free
Venom Proteomic Analysis of Two Medically Important Nigerian Viper (Echis Ocellatus and Bitis Arietans) Snake Species2021PublicationDigest preparationHILICSnake venomManualN/AHybridTrpLabel-free
Dysregulated healing responses in diabetic wounds occur in the early stages postinjury2021PublicationDigest preparationHILICMammalian tissueManualOrganicPrecipitation on-beadTrpIsobaric-tagging
Monocyte Released HERV-K dUTPase Engages TLR4 and MCAM Causing Endothelial Mesenchymal Transition2021PublicationPeptide clean-upHILICMammalian cellsManualNativeHydrophilic affinityLysC, TrpLabel-free
Proteomics of resistance to Notch1 inhibition in acute lymphoblastic leukemia reveals targetable kinase signatures2021PublicationPhosphopeptide enrichmentTi-IMAC, AmineMammalian cellsAutomatedDetergentPrecipitation on-beadLysC, TrpIsobaric-tagging, Label-free
KF Method: Automated Phosphopeptide Enrichment using MagReSyn® IMAC 2021MethodPhosphopeptide enrichmentTi-IMAC, Zr-IMACN/AAutomatedN/AN/AN/ALabel-free
High-throughput phosphoproteomics profiling of non-small cell lung cancer tissues2021PosterPhosphopeptide enrichmentTi-IMACMammalian tissueAutomatedN/AIn-solutionTrpLabel-free
The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation2021PublicationBioIDStreptavidinMammalian cellsAutomatedDetergentAffinity captureLysC, TrpLabel-free
Product Guide MagReSyn® Trypsin2021Application noteDigest preparationTrypsinN/AManualN/AIn-solutionTrpN/A
Product Guide MagReSyn® Chymotrypsin2021MethodDigest preparationChymotrypsinRecombinant protein ManualN/AIn-solutionChymoTrpN/A
Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses2021PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentPrecipitation in-solutionTrpMetabolic labelling
Drug-bound and -free outward-facing structures of a multidrug ABC exporter point to a swing mechanism2021PublicationHDXZr-IMACRecombinant protein N/AN/AN/APepsinHDX
Antagonistic cell surface and intracellular auxin signalling regulate plasma membrane H+ fluxes for root growth2021PublicationPhosphopeptide enrichmentTi-IMACPlant ManualDetergentFilter-basedTrpLabel-free
The membrane-localized protein kinase MAP4K4/TOT3 regulates thermomorphogenesis2021PublicationPhosphopeptide enrichmentTi-IMACPlant ManualNativePrecipitation in-solutionLysC, TrpLabel-free
The cGMP-Dependent Protein Kinase 2 Contributes to Cone Photoreceptor Degeneration in the Cnga3-Deficient Mouse Model of Achromatopsia2021PublicationPhosphopeptide enrichmentTi-IMACMammalian tissueManualN/APrecipitation in-solutionTrpLabel-free
Unraveling the MAX2 Protein Network in Arabidopsis thaliana: Identification of the Protein Phosphatase PAPP5 as a Novel MAX2 Interactor2021PublicationPhosphopeptide enrichmentTi-IMACPlant ManualNativeAffinity captureLysC, TrpLabel-free
An AKT2-specific nanobody that targets the hydrophobic motif induces cell cycle arrest, autophagy and loss of focal adhesions in MDA-MB-231 cells2021PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualChaotropeIn-solutionLysC, TrpLabel-free
Evaluation of Protein Purification Techniques and Effects of Storage Duration on LC-MS/MS Analysis of Archived FFPE Human CRC Tissues2021PublicationDigest preparationHILICFFPEAutomatedDetergentHydrophilic affinity TrpLabel-free
Functional studies of CpSRP54 in diatoms show that themechanism of thylakoid protein insertion differs from that inplants and green algae2021PublicationDigest preparationHILICMammalian cellsAutomatedDetergentHydrophilic affinity TrpLabel-free
Proteomic analysis of three medically important Nigerian Naja (Naja haje, Naja katiensis and Naja nigricollis) snake venoms2021PublicationDigest preparationHILICSnake venomManualN/AHydrophilic affinity TrpLabel-free
Plasmodium falciparum Calcium Dependent Protein Kinase 4 is critical for male gametogenesis and transmission to the mosquito vector2021PublicationPhosphopeptide enrichmentTi-IMAC, Zr-IMACPlasmodiumAutomatedDetergentPrecipitation in-solutionTrpLabel-free
Structural insights into an atypical secretory pathway kinase crucial for Toxoplasma gondii invasion2021PublicationPhosphopeptide enrichment, Digest preparationTi-IMAC, HILICMammalian cells, OtherManualDetergentPrecipitation on-filter, Affinity captureTrpIsobaric-tagging, Label-free
DYRK3-Controlled Phase Separation Organizes the Early Secretory Pathway2020PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsAutomatedN/AOtherTrpLabel-free
Phosphorylation controls RNA binding and transcription by the influenza virus polymerase2020PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualChaotropePrecipitation in-solutionTrpLabel-free
Modulation of immune cell reactivity with cis-binding Siglec agonists2020PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentPrecipitation on-filterTrpIsobaric-tagging
A Compact Quadrupole-Orbitrap Mass Spectrometer with FAIMS Interface Improves Proteome Coverage in Short LC Gradients2020PublicationDigest preparationAmineMammalian cells, Mammalian tissueAutomatedDetergentPrecipitation on-beadLysC, TrpLabel-free
A Compact Quadrupole-Orbitrap Mass Spectrometer with FAIMS Interface Improves Proteome Coverage in Short LC Gradients2020PublicationPhosphopeptide enrichmentTi-IMACMammalian cells, Mammalian tissueAutomatedDetergentPrecipitation on-beadLysC, TrpLabel-free
Chemical Genetics of AGC-kinases Reveals Shared Targets of Ypk1, Protein Kinase A and Sch92020PublicationPhosphopeptide enrichmentTi-IMAC, TiO2, ZrO2 Yeast cellsManualN/APrecipitation in-solutionTrpLabel-free
Rapid and site-specific deep phosphoproteome profiling by data-independent acquisition without the need for spectral libraries2020PublicationPhosphopeptide enrichmentTi-IMACYeast cellsManualDetergentPrecipitation in-solutionLysC, TrpLabel-free
Functional studies of CpSRP54 in diatoms show that the mechanism of thylakoid protein insertion differs from that in plants and green algae2020PublicationDigest preparationHILICAlgaeAutomatedDetergentHydrophilic affinityTrpLabel-free
SWATH-MS based proteomic profiling of pancreatic ductal adenocarcinoma tumours reveals the interplay between the extracellular matrix and related intracellular pathways2020PublicationDigest preparationHILICMammalian tissueAutomatedDetergentHydrophilic affinityTrpLabel-free
CDK8 fine-tunes IL-6 transcriptional activities by limiting STAT3 resident time at the gene loci2020PublicationPhosphopeptide enrichmentTi-IMACPlant ManualNativePrecipitation in-solutionLysC, TrpLabel-free
The CEP5 Peptide Promotes Abiotic Stress Tolerance, As Revealed by Quantitative Proteomics, and Attenuates the AUX/IAA Equilibrium in Arabidopsis2020PublicationPhosphopeptide enrichmentTi-IMACPlant ManualNativePrecipitation in-solutionLysC, TrpLabel-free
Alterations in the CO2 availability induce alterations in the phosphoproteome of the cyanobacterium Synechocystis sp. PCC 68032020PublicationPhosphopeptide enrichmentTi-IMAC, TiO2Bacterial cellsManualDetergentPrecipitation in-solutionLysC, TrpLabel-free
CYCA3;4 Is a Post-Prophase Target of the APC/CCCS52A2 E3-Ligase Controlling Formative Cell Divisions in Arabidopsis2020PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentN/ATrpMetabolic labelling
HIPK4 is essential for murine spermiogenesis2020PublicationPhosphopeptide enrichmentTi-IMAC, TiO2Mammalian cellsManualDetergentPrecipitation in-solutionLysC, TrpIsobaric-tagging
Fluorescence fluctuation analysis reveals PpV dependent Cdc25 protein dynamics in living embryos2020PublicationPhosphopeptide enrichmentTi-IMACDrosophilaManualNativeGel-basedTrp (in-gel)Label-free
Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B2020PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsAutomatedDetergentPrecipitation in-solutionLysC, TrpIsobaric-tagging
Cannabinoid exposure in rat adolescence reprograms the initial behavioral, molecular, and epigenetic response to cocaine2020PublicationPhosphopeptide enrichmentTi-IMAC, Zr-IMACMammalian tissueManualChaotropePrecipitation in-solutionLysC, TrpIsobaric-tagging
The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress2020PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentFilter-basedN/ALabel-free
Phosphoproteomic Effects of Acute Depletion of PP2A Regulatory Subunit Cdc2020PublicationPhosphopeptide enrichmentTi-IMAC, TiO2, ZrO2Yeast cellsManualChaotropeIn-solutionLysC, TrpMetabolic labelling
An Unbiased Approach to Mapping the Signaling Network of the Pseudorabies Virus US3 Protein2020PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualChaotropeIn-solutionLysC, TrpLabel-free
Zirconium(IV)-IMAC Revisited: Improved Performance and Phosphoproteome Coverage by Magnetic Microparticles for Phosphopeptide Affinity Enrichment2020PublicationPhosphopeptide enrichmentTi-IMAC, Zr-IMAC, TiO2 Mammalian cellsBothDetergentPrecipitation in-solutionTrpLabel-free
Parallel global profiling of plant TOR dynamics reveals a conserved role for LARP1 in translation2020PublicationPhosphopeptide enrichmentTiO2Plant ManualNativeIn-solutionTrpIsobaric-tagging
Magnetic micro-macro biocatalysts applied to industrial bioprocesses2020PublicationImmobilizationNi-NTARecombinant protein ManualN/AN/AN/AN/A
Magnetic micro-macro biocatalysts applied to industrial bioprocesses2020PublicationImmobilizationAmineRecombinant protein ManualN/AN/AN/AN/A
Novel kinase platform for the validation of the anti-tubercular activities of Pelargonium sidoides (Geraniaceae)2020PublicationProtein PurificationNi-NTABacterial cellsManualNativeN/AN/AN/A
Product Guide MagReSyn® TiO22020MethodPhosphopeptide enrichmentTiO2N/AManualN/AN/AN/ALabel-free
Evaluation of Novel Supports for Selective and Efficient Enrichment of Phosphorylated Peptides2020MethodPhosphopeptide enrichmentTiO2, ZrO2N/AAutomatedN/AN/AN/ALabel-free
Parallel global profiling of plant TOR dynamics reveals a conserved role for LARP1 in protein translation2020PublicationPhosphopeptide enrichmentTiO2Plant ManualNativeIn-solutionTrpIsobaric-tagging
Product Guide MagReSyn® ZrO22020MethodPhosphopeptide enrichmentZrO2N/AManualN/AN/AN/ALabel-free
Product Guide MagReSyn® Ti-IMAC HP2020MethodPhosphopeptide enrichmentTi-IMACN/AManualN/AN/AN/ALabel-free
Product Guide MagReSyn® Ti-IMAC2020MethodPhosphopeptide enrichmentTi-IMACN/AManualN/AN/AN/ALabel-free
A Data Independent Acquisition Workflow Enables the Profiling of Thousands of Human Cancer Tissues for Precision Oncology2020PosterPhosphopeptide enrichmentTi-IMACMammalian tissueAutomatedUnknownIn-solutionTrpLabel-free
Fast and reproducible phosphoproteomics using MagReSyn® Amine and Ti-IMAC HP magnetic beads and the Evosep One2020Application notePhosphopeptide enrichmentTi-IMACMammalian cellsAutomatedDetergentPrecipitation on-beadLysC, TrpLabel-free
Fast and reproducible phosphoproteomics using MagReSyn® Amine and Ti-IMAC HP magnetic beads and the Evosep One2020Application noteDigest preparationAmineMammalian cellsAutomatedDetergentPrecipitation on-beadLysC, TrpLabel-free
High Throughput Proteome and Phosphoproteome Sample Processing Couple to Fast Gradient DIA2020PosterPhosphopeptide enrichmentTi-IMACMammalian tissueAutomatedDetergentPrecipitation on-beadLysC, TrpLabel-free
High Throughput Proteome and Phosphoproteome Sample Processing Couple to Fast Gradient DIA2020PosterDigest preparationAmineMammalian tissueAutomatedDetergentPrecipitation on-beadLysC, TrpLabel-free
Product Guide MagReSyn® Zr-IMAC HP2020MethodPhosphopeptide enrichmentZr-IMACN/AManualN/AN/AN/ALabel-free
Product Guide MagReSyn® Zr-IMAC2020MethodPhosphopeptide enrichmentZr-IMACN/AManualN/AN/AN/ALabel-free
Zirconium(IV) IMAC-based enrichment for mass spectrometry driven phosphoproteomics2020PosterPhosphopeptide enrichmentTi-IMAC, Zr-IMACMammalian cellsAutomatedN/AN/AN/ALabel-free
KF Method: Automated clean-up and on-bead digestion with MagReSyn® HILIC2020MethodDigest preparationHILICN/AAutomatedDetergentHydrophilic affinity TrpLabel-free
Sustainable synthesis of uridine-5?-monophosphate analogues by immobilized uracil phosphoribosyltransferase from Thermus thermophilus2020PublicationImmobilizationAmineRecombinant protein ManualN/AN/AN/AN/A
Identification of MAMP-Responsive Plasma Membrane-Associated Proteins in Arabidopsis thaliana Following Challenge with Different LPS Chemotypes from Xanthomonas campestris2020PublicationAffinity captureStreptavidinBacterial cellsManualN/AN/AN/AN/A
Biochemical Pulldown of mRNAs and Long Noncoding RNAs from Cellular Lysates Coupled with Mass Spectrometry to Identify Protein Binding Partners2020PublicationAffinity captureStreptavidinMammalian cellsManualDetergentGel-basedTrpLabel-free
Multiplexed Proximity Biotinylation Coupled to Mass Spectrometry for Defining Integrin Adhesion Complexes2020PublicationBioIDStreptavidinMammalian cellsManualDetergentGel-basedTrpLabel-free
Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation2020PublicationBioIDStreptavidinMammalian cellsManualDetergentGel-basedTrpLabel-free
BioID based proteomic analysis of the Bid interactome identifies novel proteins involved in cell cycle dependent apoptotic priming2020PublicationBioIDStreptavidinMammalian cellsManualDetergentGel-basedTrpLabel-free
Plant-based production of highly potent anti-HIV antibodies with engineered posttranslational modifications2020PublicationAffinity captureProtein APlant ManualNativeN/AN/AN/A
Hypoxia regulates GR function through multiple mechanisms involving microRNAs 103 and 1072020PublicationChIPProtein GMammalian cellsManualN/AN/AN/AqPCR
Insights from the First Phosphopeptide Challenge of the MS Resource Pillar of the HUPO Human Proteome Project2020PublicationPhosphopeptide enrichmentTi-IMACHUPO SyntheticBothN/AN/AN/AN/A
Evaluation of Protein Purification Techniques and Effects of Storage Duration on LC-MS/MS Analysis of Archived FFPE Human CRC Tissues2020PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentPrecipitation on-filterTrpIsobaric-tagging
Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis2019PublicationPhosphopeptide enrichmentTi-IMACMammalian tissueManualChaotropePrecipitation in-solutionTrp double digestIsobaric-tagging
Proteasome-mediated remodeling of the proteome and phosphoproteome during kiwifruit pollen germination2019PublicationPhosphopeptide enrichmentTi-IMACPlant ManualN/AHybridN/ALabel-free
Conduit integrity is compromised during acute lymph node expansion2019PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsAutomatedChaotropeFilter-basedN/AIsobaric-tagging
Probability-based detection of phosphoproteomic uncertainty reveals rare signaling events driven by oncogenic kinase gene fusion2019PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentPrecipitation in-solutionTrpLabel-free
CDK8 Regulates Insulin Secretion and Mediates Postnatal and Stress-Induced Expression of Neuropeptides in Pancreatic ? Cells2019PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentFilter-basedN/ALabel-free
Protein Aggregation Capture on Microparticles Enables Multipurpose Proteomics Sample Preparation2019PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentPrecipitation on-beadLysC, TrpLabel-free
R2-P2 rapid-robotic phosphoproteomics enables multidimensional cell signaling studies2019PublicationPhosphopeptide enrichmentTi-IMAC, Zr-IMAC, TiO2Yeast cellsAutomatedChaotropePrecipitation on-beadLysC, TrpLabel-free
Development of fully automated pipeline for phosphoproteome profiling optimisation of phosphopeptide enrichment2019PosterPhosphopeptide enrichmentTi-IMAC, Zr-IMAC, TiO2, ZrO2, Amine, HILIC, SAXRecombinant protein, Mammalian cellsAutomatedDetergent, ChaotropeIn-solution, Precipitation on-bead, Hydrophilic affinity, Ion exchangeTrpIsotope-labelled peptides, Label-free
Development of a fully automated high throughput magnetic workflow for phosphoproteome profiling2019PosterPhosphopeptide enrichmentTi-IMAC, Zr-IMAC, TiO2Mammalian cellsAutomatedDetergentPrecipitation on-beadTrpLabel-free
Development of fully automated pipeline for phosphoproteome profiling2019PosterPhosphopeptide enrichment, Digest preparationTi-IMAC, SAX, HILICMammalian cellsAutomatedDetergent, ChaotropePrecipitation on-bead, Hydrophilic affinity, Ion exchange TrpLabel-free
PEPCLU MagReSyn HILIC Clean-Up of Peptides Post Protein Digestion2019MethodPeptide clean-upHILICN/AManualDetergentHydrophilic affinity N/ALabel-free
RAPOBD HILIC Clean-Up of Reduced & Alkylated Proteins with on Bead Digestion2019MethodDigest preparationHILICMammalian cellsManualDetergentHydrophilic affinity TrpLabel-free
POBRAD HILIC Clean-Up of proteins with on-bead reduction, alkylation and digestion2019MethodDigest preparationHILICMammalian cellsManualDetergentHydrophilic affinity TrpLabel-free
Preparation and HILIC SPE clean-up of SDS extracted plasma proteins for MS analysis2019MethodDigest preparationHILICBiofluidsManualDetergentHydrophilic affinity TrpLabel-free
Improved reproducibility of automated sample preparation using HILIC magnetic beads automated by Hamilton Robotics2019Application noteDigest preparationHILICN/AAutomatedDetergentHydrophilic affinity TrpLabel-free
Development of a fully automated magnetic workflow for phosphoproteome profiling2019PosterPhosphopeptide enrichment, Digest preparationTi-IMAC, Zr-IMAC, TiO2, ZrO2, SAX, HILICMammalian cellsAutomatedDetergent, ChaotropeHydrophilic affinity, Ion exchangeTrpLabel-free
Product Guide MagResyn® Amine - activation with epoxide for protein immobilization2019MethodImmobilizationAmineN/AManualN/AN/AN/AN/A
Product Guide MagReSyn® Streptavidin2019MethodAffinity captureStreptavidinN/AManualN/AN/AN/AN/A
Product Guide MagReSyn® Streptavidin MAX2019MethodAffinity captureStreptavidinN/AManualN/AN/AN/AN/A
Product Guide MagReSyn® Protein A2019MethodAffinity captureProtein AN/AManualN/AN/AN/AN/A
Product Guide MagReSyn® Protein A MAX2019MethodAffinity captureProtein AN/AManualN/AN/AN/AN/A
Product Guide MagReSyn® Protein G2019MethodAffinity captureProtein GN/AManualN/AN/AN/AN/A
p38α MAPK proximity assay reveals a regulatory mechanism of alternative splicing in cardiomyocytes2019PublicationAffinity captureProtein GMammalian tissueManualDetergentGel-basedN/AN/A
An improved method for quantitative ChIP studies of nuclear receptor function2019PublicationChIPProtein GMammalian tissueManualN/AIn-solutionN/AqPCR
The Auxin-Regulated CrRLK1L Kinase ERULUS Controls Cell Wall Composition during Root Hair Tip Growth2018PublicationPhosphopeptide enrichmentTi-IMACPlant ManualNativePrecipitation in-solutionLysC, TrpLabel-free
Ultra-High Pressure (>30,000 psi) Packing of Capillary Columns Enhancing Depth of Shotgun Proteomic Analyses2018PublicationPhosphopeptide enrichmentTi-IMACMammalian cells, Mammalian tissueManualChaotropePrecipitation in-solutionLysC, TrpIsobaric-tagging
Magnetic HILIC: An enabling & versatile tool for robust automated MS sample preparation workflows2018PosterDigest preparationHILICMammalian cellsAutomatedDetergentHydrophilic affinity TrpLabel-free
Magnetic HILIC: An enabling & versatile tool for robust automated MS sample preparation workflows2018PosterPeptide clean-upHILICMammalian cellsAutomatedDetergentHydrophilic affinity TrpLabel-free
Enzymatic and Chemical Synthesis of Nucleic Acid Derivatives2018PublicationImmobilizationAmineRecombinant protein ManualN/AN/AN/AN/A
Enzymatic Synthesis of Therapeutic Nucleosides using a Highly Versatile Purine Nucleoside 2’-DeoxyribosylTransferase from Trypanosoma brucei2018PublicationImmobilizationAmineRecombinant protein ManualN/AN/AN/AN/A
One-Pot, One-Step Production of Dietary Nucleotides by Magnetic Biocatalysts2018PublicationImmobilizationAmineRecombinant protein ManualN/AN/AN/AN/A
Immune genes are primed for robust transcription by proximal long noncoding RNAs located in nuclear compartments2018PublicationAffinity captureStreptavidin, Protein A, Protein GMammalian cellsManualDetergentGel-basedN/AqPCR
REVERBa couples the circadian clock to hepatic glucocorticoid action2018PublicationChIP, Affinity captureProtein A, Protein GMammalian cellsManualN/AN/AN/AqPCR
LRP1 is required for novobiocin-mediated fibronectin turnover2018PublicationAffinity captureProtein AMammalian cellsManualDetergentGel-basedTrpN/A
Circadian clock component REV-ERB? controls homeostatic regulation of pulmonary inflammation2018PublicationAffinity captureProtein AMammalian cellsManualDetergentGel-basedTrpN/A
Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation2017PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsAutomatedDetergentPrecipitation in-solutionTrp, AspN Isobaric-tagging
Phosphoproteomics with Activated Ion Electron Transfer Dissociation2017PublicationPhosphopeptide enrichmentTi-IMACMammalian tissueManualChaotropePrecipitation in-solutionTrpLabel-free
Proteome Profiling of Wheat Shoots from Different Cultivars2017PublicationPhosphopeptide enrichmentTi-IMACPlant ManualNativePrecipitation in-solutionLysC, TrpLabel-free
GSK3α and GSK3β Phosphorylate Arc and Regulate its Degradation2017PublicationPhosphopeptide enrichmentTi-IMACRecombinant protein ManualDetergentOtherTrp, PepsinLabel-free
Identification of ADP-Ribose Acceptor Sites on In Vitro Modified Proteins by Liquid Chromatography–Tandem Mass Spectrometry2017PublicationADP-ribosylation enrichmentTi-IMACRecombinant protein ManualChaotropeFilter-basedTrpLabel-free
Cell-Specific Labeling for Analyzing Bidirectional Signaling by Mass Spectrometry2017PublicationPhosphopeptide enrichmentTi-IMAC, TiO2Mammalian cellsManualChaotropeFilter-basedTrpMetabolic labelling
Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development2017PublicationPhosphopeptide enrichmentTi-IMACC. elegansAutomatedChaotropeIn-solutionLysC, TrpLabel-free
HIV-1 Activates T Cell Signaling Independently of Antigen to Drive Viral Spread2017PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentFilter-basedTrp double digestMetabolic labelling
Proteomic analysis of cell cycle progression in asynchronous cultures, including mitotic subphases, using PRIMMUS2017PublicationPhosphopeptide enrichmentTi-IMACMammalian cellsManualDetergentPrecipitation on-beadLysC, TrpIsobaric-tagging
Reactivation of MagReSyn® Ti-IMAC2017MethodPhosphopeptide enrichmentTi-IMACN/AN/AN/AN/AN/AN/A
Product Guide MagReSyn® HILIC2017MethodDigest preparationHILICN/AManualDetergentHydrophilic affinity TrpLabel-free
Universal Unbiased pre-MS Clean-Up Using Magnetic HILIC Microparticles for SPE2017PosterDigest preparationHILICMammalian cellsAutomatedDetergentHydrophilic affinity TrpLabel-free
Dealing with the Dirty Dozen: Universal Unbiased preMS Clean-Up Using Magnetic HILIC SPE2017PosterDigest preparationHILICMammalian cellsAutomatedDetergentHydrophilic affinity TrpLabel-free
Product Guide MagReSyn® Amine2017MethodImmobilizationAmineN/AManualN/AN/AN/AN/A
Structural and functional characterization of thermostable biocatalysts for the synthesis of 6-aminopurine nucleoside-5?-monophospate analogues2017PublicationImmobilizationAmineRecombinant protein ManualN/AN/AN/AN/A
Product Guide MagReSyn® Carboxyl2017MethodImmobilizationCarboxylRecombinant protein ManualN/AN/AN/AN/A
Identification of lipopolysaccharide-interacting plasma membrane-type proteins in Arabidopsis thaliana2017PublicationAffinity captureStreptavidinPlant ManualNativeGel-basedTrpN/A
Up-to-Date Workflow for Plant (Phospho)proteomics Identifies Differential Drought-Responsive Phosphorylation Events in Maize Leaves2016PublicationPhosphopeptide enrichmentTi-IMACPlant ManualNativePrecipitation in-solutionLysC, TrpLabel-free
Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation2016PublicationPhosphopeptide enrichmentTi-IMAC, TiO2Mammalian cellsAutomatedAutomatedNaPPiTrpIsobaric-tagging
The co-immobilization of P450-type nitric oxide reductase and glucose dehydrogenase for the continuous reduction of nitric oxide via cofactor recycling2016PublicationImmobilizationAmineRecombinant protein ManualN/AN/AN/AN/A
The co-immobilization of P450-type nitric oxide reductase and glucose dehydrogenase for the continuous reduction of nitric oxide via cofactor recycling2016PublicationImmobilizationCarboxylRecombinant protein ManualN/AN/AN/AN/A
An Unbiased Mass Spectrometry Approach Identifies Glypican-3 as an Interactor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR) in Hepatocellular Carcinoma Cells2016PublicationAffinity captureProtein GMammalian cellsManualNativeGel-basedTrpN/A
Phosphoproteomic analysis of interacting tumor and endothelial cells identifies regulatory mechanisms of transendothelial migration2016PublicationAffinity captureProtein AMammalian cellsManualDetergentN/AN/AN/A
Comprehensive protein sequence coverage using MagReSyn® Trypsin & MagReSyn® Chymotrypsin2016Application noteDigest preparationTrypsinRecombinant protein AutomatedChaotropeIn-solutionTrpLabel-free
Comprehensive protein sequence coverage using MagReSyn® Trypsin & MagReSyn® Chymotrypsin2016Application noteDigest preparationChymotrypsinRecombinant protein AutomatedChaotropeIn-solutionChymoTrpLabel-free
Improved stability of MagReSyn® Trypsin in the presence of denaturants: SDS and Urea 2016Application noteDigest preparationTrypsinRecombinant protein ManualChaotropeIn-solutionTrpLabel-free
Efficient purification of polyhistidinetagged proteins under denaturing conditions using MagReSyn® NTA Inclusion bodies & hidden tags2015Application noteProtein PurificationNi-NTABacterial cellsManualChaotropeN/AN/AN/A
MagReSyn NTA Increased purity of histidine-tagged proteins through enhanced binding affinity2015Application noteProtein PurificationNi-NTABacterial cellsManualNativeN/AN/AN/A
Product Guide MagReSyn® NTA Screening Kit2015MethodProtein PurificationNTA-KitBacterial cellsManualNativeN/AN/AN/A
Product Guide MagReSyn® NTA2015MethodProtein PurificationNi-NTABacterial cellsManualNativeN/AN/AN/A
A colorimetric-based amplification system for proteinases including MMP2 and ADAM82015PublicationImmobilizationNi-NTAMammalian cellsManualNativeN/AN/AN/A
Product Guide MagReSyn® SAX2015MethodProtein PurificationSAXN/AManualNativeN/AN/AN/A
Immobilization of thermostable nucleoside phosphorylases on MagReSyn® epoxide microspheres and their application for the synthesis of 2,6-dihalogenated purine nucleosides2015PublicationImmobilizationAmineRecombinant protein ManualN/AN/AN/AN/A
Synthesis of 2,6-Dihalogenated Purine Nucleosides by Thermostable Nucleoside Phosphorylases2015PublicationImmobilizationAmineRecombinant protein ManualN/AN/AN/AN/A
Ultrasensitive proteome analysis using paramagnetic bead technology2015PublicationDigest preparationCarboxylDrosophilaManualDetergentPrecipitation on-beadTrpLabel-free
Reproducible Automated Phosphopeptide Enrichment Using Magnetic TiO2 and Ti-IMAC2014PublicationPhosphopeptide enrichmentTi-IMAC, TiO2Mammalian cellsAutomatedN/AFilter-basedLysC, TrpMetabolic labelling
Cell-specific Labeling Enzymes for Analysis of Cell–Cell Communication in Continuous Co-culture2014PublicationPhosphopeptide enrichmentTi-IMAC, TiO2Mammalian cellsManualChaotropeFilter-basedLysC, TrpMetabolic labelling
Spectrophotometric activity microassay for pure and recombinant cytochrome P450-type nitric oxide reductase2014PublicationProtein PurificationNi-NTABacterial cellsManualDetergentN/AN/AN/A
Robotic Platform for Parallelized Cultivation and Monitoring of Microbial Growth Parameters in Microwell Plates2014PublicationProtein PurificationNi-NTABacterial cellsAutomatedNativeN/AN/AN/A
Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp702014PublicationAffinity captureStreptavidinMammalian tissueManualNativeIn-solutionN/AN/A