MagReSyn® Streptavidin

High capacity for capture of biotinylated molecules

MagReSyn® Streptavidin microparticles contain covalently coupled streptavidin. The porous nature of the polymer technology allows for exceptional streptavidin capacity, translating into increased capacity for the immobilization/capture of biotinylated biomolecules. The high streptavidin load allows the use of as little as 10 µl beads, improving experimental miniaturization for high-throughput automated analysis. Molecular applications of MagReSyn® Streptavidin microparticles include, protein immobilization and purification; nucleic acid capture assays and preparation of single-stranded DNA templates for e.g. SELEX and pyrosequencing. The immobilization of biotinylated antibodies may subsequently be used in e.g. immunoassay.

Support: Proprietary polymer microparticles containing iron oxide (magnetite) with immobilised Streptavidin
Binding capacity (DNA): > 30 000 pmoles.ml-1 (Biotinylated oligo, 25-mer)
Binding capacity (Protein): > 3 mg.ml-1 (Biotinylated IgG)
Bead size: ~5-10 µm average
Formulation: 10 mg.ml-1 suspension in sodium phosphate buffer

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MagReSyn® Streptavidin MAX

Ultra-capacity for capture of biotinylated molecules

MagReSyn® Streptavidin MAX microparticles have been specially engineered for custom applications where maximum binding of biotinylated molecules is required. This includes microplate applications where miniaturization and high-throughput automated analysis are required. This product primarily targeted for oligo/peptide isolation, and it is not recommended for protein isolation due to possible steric hindrance with the high streptavidin load. 

Binding capacity (DNA): > 120 000 pmoles.ml-1 (Biotinylated oligo, 25-mer)
Bead size: ~5-10 µm
Formulation: 10 mg.ml-1 suspension in sodium phosphate buffer

* Please note that MagReSyn® Streptavidin MAX is a custom product with minimum 2 weeks lead time from date of order *

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Streptavidin protein image courtesy of ebi.ac.uk accession number 5n8b, and used for illustration purposes only.

Product Resources

MagReSyn® Streptavidin Performance Superiority

Superior capacity

MagReSyn® Streptavidin

  • >3 000 pmoles.mg-1 (Biotinylated oligo, 25-mer)
  • >300 µg.mg-1 (Biotinylated IgG)

MagReSyn® Streptavidin MAX

  • MAX: >12 000 pmoles.mg-1 

High volumetric streptavidin loading allows unparalleled miniaturization and automation of experimentation

Exceptional Capacity

High capacity for biotinylated protein enables miniaturization of experimentation.

Exceptional Value

  • Bind in excess of 3000 µg biotinylated IgG compared to alternate products
  • Bind in excess of 60 000 pmoles biotinylated oligo per product compared to 25 000 pmoles biotinylated oligo per product for alternate products

MagReSyn® Streptavidin microparticles provide superior binding capacity for biotinylated oligos and protein compared to alternate suppliers. MagReSyn® Streptavidin MAX provides an high capacity for biotinylated oligo and protein binding for specialized applications. Green bars represent MagReSyn®, orange bars represent alternate suppliers products.

Citation and Reference Examples

Please review our comprehensive method library to find the most relevant reference material for your particular application.

Bromodomain factor 5 is an essential regulator of transcription in Leishmania

–   Nathaniel G. Jones et al.

Nature Communications, 2022

MagReSyn® Streptavidin & MagReSyn® Ti-IMAC

ULK4 and Fused/STK36 interact to mediate assembly of a motile flagellum

–  Ciaran J McCoy et al.

BioRxiv, 2022

MagReSyn® Streptavidin

A heparan-sulfate-bearing syndecan-1 glycoform is a distinct surface marker for intra-tumoral myeloid-derived suppressor cells

–  Thomas Welte et al.

Cell iScience, 2021

MagReSyn® Streptavidin

Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1

–   Rosemary E Gough et al.

JBC, 2021

MagReSyn® Streptavidin

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation

–   Jordan M Meyers et al.

PLOS Pathogens, 2021

MagReSyn® Streptavidin

Biochemical Pulldown of mRNAs and Long Noncoding RNAs from Cellular Lysates Coupled with Mass Spectrometry to Identify Protein Binding Partners

–   Anca F. Savalescu et al.

Bio-Protocol, 2020

MagReSyn® Streptavidin

TERMS AND CONDITIONS
Products supplied by ReSyn Biosciences (Pty) Ltd are for research purposes only. ReSyn products are not to be used for diagnostic, therapeutic or commercial means any use resulting in monetary gain, including, but not limited to, incorporation in a kit, repackaging and re-formulation. Please enquire about sub-licenses for commercial use.