Products supplied by ReSyn Biosciences (Pty) Ltd are for research purposes only. ReSyn products are not to be used for diagnostic, therapeutic or commercial purposes. Commercial means any use resulting in monetary gain, including, but not limited to, incorporation in a kit, repackaging and re-formulation. Please enquire about sub-licenses for commercial use.
Support: Proprietary polymer microspheres containing iron oxide (magnetite) Binding capacity: > 10 µg phosphopeptide per mg support Bead size: 5-10 µm average Formulation: 20 mg.ml-1 suspension in 20% ethanol
Magnetic microspheres with chelated Ti4+ metal ions for highly-specific phosphopeptide enrichment
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Protein phosphorylation is one of the most important post-translational modifications and is a critical process in cellular signaling and regulation of cellular networks. Comprehensive analysis of the phosphoproteome is a challenging task due to the transient and sub-stoichiometric nature of phosphorylation sites. High-throughput phosphoproteome analysis by mass spectrometry requires compatible technologies than can specifically enrich phosphopeptides. MagReSyn® Ti-IMAC microspheres have a flexible linker (to reduce steric hindrance) activated with phosphonate groups for Ti4+ chelation. The unique properties of the proprietary ReSyn microsphere technology allows extremely specific, reproducible enrichment of phosphopeptides from complex biological samples/protein digests. The microspheres can be used either alone, or in combination with MagReSyn® TiO2, MagReSyn® Zr-IMAC and/or MagReSyn® ZrO2 to increase phosphoproteome coverage.
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Click HERE for literature on Reproducible Automated Phosphopeptide Enrichment using MagReSyn® Ti-IMAC
MagReSyn® Ti-IMAC
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PLEASE NOTE: This product has a limited shelf life of 6 months; please carfefully consider your order quantity as the product performance cannot be guaranteed beyond the 6 months shelf life.